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CBD has received an enormous amount of attention lately. In fact, it seems not a day goes by without some mention of CBD on social media, the news, or elsewhere.

But what exactly has fueled this interest in CBD? In this article, we explore some of the main reasons CBD has become increasingly popular in recent years.

The Story Of Charlotte’s Web

Undoubtedly, one of the most influential catalysts leading to CBD’s rise in popularity was the release of a 2013 news report on “Charlotte’s Web.”

Charlotte’s Web is a potent CBD extract manufactured by the Stanley Brothers from Colorado, USA. It is named after Charlotte Figi, a young girl from Boulder, Colorado, who uses the oil for severe epileptic seizures.

Charlotte’s story first made headlines in 2013, after CNN published an in-depth report exploring the ameliorative potential of CBD, especially for seizures and tremors caused by severe forms of epilepsy like Dravet Syndrome.

This report shined a global spotlight not only on Charlotte and other children like her, but also on CBD specifically. Since its broadcast in 2013, countless other reports have further explored CBD, it’s chemical makeup, effects on the body, and therapeutic potential.

Increased Research

Another major factor influencing the rise of CBD is an increase in scientific research of cannabis and hemp plants.

While humans have used cannabis for thousands of years, it is only in the last few years that we’ve really begun understanding the plant, its many compounds, and the effects they can have on the human body.

For example, THC (the main psychoactive ingredient in cannabis) was only isolated from the plant in 1964 (just over 50 years ago); human cannabinoid receptors and endogenous cannabinoids (like anandamide and 2-AG) were only discovered in the late 1980s and early 1990s.

Ever since, a growing body of research has tried to better understand cannabis. This research has not only helped the general populace better understand the cannabis plant, it has built up a lot of awareness about specific compounds, such as CBD.

Legality And Accessibility

Legality is a big topic in the cannabis industry. “Legalize cannabis” campaigns have gained a lot of momentum across the world, which is another major reason CBD and other cannabinoids have become more widespread.

This is mainly because CBD, unlike THC, is less restricted in many countries. This is largely due to the fact that CBD is a non-psychoactive cannabinoid, meaning it doesn’t interfere with normal physical or psychological functioning.

In the US, for example, CBD products with less than 1% THC are completely legal and can be purchased online and shipped virtually all around the country.

The same is true in many European countries. In Switzerland, for example, products like hemp cigarettes containing 4mg of CBD can be purchased like regular cigarettes and tobacco products at supermarkets and kiosks.

The fact that CBD is less restricted than THC and other cannabinoids makes it much more appealing for consumers looking to use cannabis and hemp products. It also makes it much easier to ship and market these products, making them more accessible.

Increased Market Size

Another contributing factor to CBD’s boom is increased market size.

The cannabis industry, in general, is already experiencing massive growth. In the US, for example, it is estimated to be worth over USD $20 billion by 2020. But the demand for CBD products is especially high. The market for CBD-rich hemp and hemp-derived products is already valued at roughly USD $130 million according to a 2016 market estimate by Vote Hemp and the Hemp Business Journal.

The United States is seeing a big increase in CBD companies, offering everything from food supplements (like hemp seed), to products like CBD-rich tinctures, to cosmetics, body creams, lotions, and more.

In Europe, the demand for CBD is pegged at roughly €2 billion, according to research by nova-Institute and HempConsult, two German companies who researched the European market potential for non-psychoactive CBD products.

This growing market size directly stimulates the popularity of CBD. With more companies and products on the market, customers are being presented with more information about CBD and its many potential uses.

Increased Awareness

All of the factors we’ve discussed in this article so far (increased research, improved accessibility, and bigger market size) are significant on their own. However, together they work to generally increase awareness of CBD on a global scale.

The research into CBD, for example, is fueling countless media reports on new scientific studies exploring every aspect of this unique chemical.

Meanwhile, the fact that CBD is accessible and legal makes it easier for consumers to experiment with CBD products and try them out for themselves. The growing market potential also means that companies and other interested groups are putting together more information about CBD and making it regularly available.

And in today’s day and age, it’s easier than ever before to disseminate that information and reach a global audience. Through increased media attention and the rise of social media, people are coming into contact with CBD-related information on a daily basis, regardless of where they live.

CBD Is Extremely Versatile

Last, but not least, one of the main reasons CBD has become so popular is because of its versatility.

For some, it’s an important nutritional supplement; for others, a new addition to their health and beauty routine.

To find out more about CBD and how it can help you improve different aspects of your life, check out our website and place your order today.

Source: Cibdol©

Researchers are working on cannabinoids to target both diabetes causes and symptoms. The maintenance of a stable homeostatic environment in our body seems to be the key for novel cannabis treatment against diabetes. A cure is yet to come, but some symptoms may be mitigated with cannabis flowers and extracts.

Diabetes is a set of metabolic diseases derived by the body’s inability in regulating the amount of sugars, particularly glucose, in blood. Glucose levels are regulated by hormones such as insulin, produced in the pancreas. Diabetes can cause long-term complications like cardiovascular disease, stroke, damages to kidneys and eyes.

The cannabinoid system is involved in the bloodsuger affair

A growing body of research is confirming the anecdotal evidence built among diabetes patients, showing that cannabis can have beneficial effects. THC and CBD anti-inflammatory action may help with the arterial inflammation, which is common in diabetes, while the neuroprotective effect can reduce inflammation of nerves and related pain. Cannabinoids can also act as vasodilators, improving blood circulation and exerting an anti-spasmodic action on muscle cramps and gastrointestinal disorders. The typical diabetic restless syndrome might also be addressed with cannabis to help patients sleep better. Recent lab studies are also showing that the endocannabinoid system could actually be targeted to stabilize the blood sugar level, thus pointing at the core of the disease. Unfortunately that’s lab research. There isn’t any cannabis therapy today conceivable against diabetes.

Diabetic mice get better with cannabis in laboratories

Though lacking clinical research on human patients, lab experiments demonstrate a strict correlation between diabetes’ activity and cannabinoids. One of the first studies evidencing the influence of the endocannabinoid system on diabetes was published in 2006 with the title “Cannabidiol lowers incidence of diabetes in non-obese diabetic mice”. This study was indicating that CBD can inhibit and delay destructive insulitis and inflammatory cytokine production, resulting in a decreased incidence of diabetes.

Researchers also wrote about a possible specific immunomodulatory mechanism activated by CBD. That hypothesis is confirmed by other findings about cannabidiol, arresting the onset of autoimmune diabetes in mice, and by one study that discovered some neuroprotective effects of CBD in an experimental model of diabetes. A research also finds that CBD attenuates cardiac dysfunction in diabetic cardiomyopatic mice.

A study titled “Marijuana in the Management of Diabetes” was published in the American Journal of Medicine in 2013. In this report, past and current cannabis use was associated with lower levels of fasting insulin, blood glucose, and insulin resistance. According to this study, cannabis users are less likely to become obese, and have lower body mass index measurements. Cannabis smokers also had higher levels of “good cholesterol” and smaller waist circumference. An important finding of this research is that cannabis users appeared to have better carbohydrate metabolism than non-users, which is kind of confirming the lab test results we have seen before.

One of the latest important studies dates back in 2015, when scientists led by Raphael Mechoulam, well known for discovering CBD, showed that the anti-inflammatory properties of cannabidiol could be used to treat different illnesses, including type 2 diabetes. Finally, **an October 2016 research showed that an experimental CBD treatment reduced the markers of inflammation in the microcirculation of the pancreas in mice. All these studies conclude that cannabis compounds have a role in controlling blood sugar levels and in mitigating pain or other symptoms of diabetes. We still don’t know how to make a medicine from these findings.

A study from October 2016

Mitigating thesymptoms of diabetes with CBD

Out of the labs and into patients’ houses, there is a whole body of evidence showing that cannabis is effective in treating eye disorders, chronic pain, sleep disorders, and other ailments associated with diabetes. The way people are treated for diabetes also depends on whether or not the person has additional complications, and their general health. Some patients are complementing their therapies with cannabinoids.

Cannabis may initially promote appetite and overeating, yet in the long run it has the opposite effect, and may even protect against obesity. Cannabis extracts with different proportions between THC, CBD, other cannabinoids and terpenes, or just containing the non-psychotropic CBD can benefit cardiac and arterial health. The same hemp or cannabis extracts can be used to make topical creams to relieve neuropathic pain. Conversely, a possible risk of cannabis use with diabetes is hypoglycaemia, as there are some concerns that glucose levels might drop unnoticed by the patient until they are in dangerous territory.

Any form of exercise on a regular basis, together with a healthy, well-balanced diet can reduce the risk of developing diabetes and control blood sugar levels in persons with this disease. Diabetes patients should also moderate or quit smoking and drinking alcohol.

Source: Cibdol©

CBD stands for Cannabidiol and THC stands for tetrahydrocannabidiol. They are both key ingredients in marijuana plants. Cannabinoids are a unique class of compounds and both CBD and THC belong to this class. High THC strains are common when it comes to marijuana but strains with high CBD are rare. The following are a few key differences found between CBD and THC.

What is CBD?

Cannabis has more than 60 cannabinoids and CBD [1] is one of them. It is usually marketed in chewable, cream and liquid forms on its own. It interacts with the receptor cells and boosts the response of the nervous system in the human body. Human body has two cannabinoid receptors – CB-1 and CB-2. It is also a natural suppressant.

What is THC?

THC [2] is not only one of the 60 cannabinoids but it is also the major psychoactive ingredient found in cannabis. THC happens to be the most researched and popularly recognized compounds of cannabis. It interlocks with the nerve cell receptors but the reaction is quite different from that of drugs like morphine and heroin. Dopamine is released as a result of THC’s interaction with the brain. The effects of THC last for 2 hours. The effects start within 10 – 30 minutes of ingestion.

High

Marijuana’s most psychoactive ingredient is probably THC but CBD, on the other hand, is completely non-psychoactive. This is why THC gives users a high effect while CBD does not. This is why recreational users never prefer CBD but its non-psychoactive properties have made it a good candidate for medical research.

Anxiety and Paranoia Related Side Effects

Paranoia and anxiety are some side-effects of using THC which many users have experienced. On the other hand, CBD has fared better in this area. A scientific paper [3] studied the psychotomimetic effects of both CBD and THC in 134 users and CBD showed no results related to causing paranoia and anxiety.

Antipsychotic

THC has effects similar to psychosis. On the other hand, CBD is non-psychoactive and also helps to counteract the psychoactive effects of THC. A research paper [4] showed that CBD had properties to reduce the high of users because of its antipsychotic capability. CBD as one of the active compounds in various pharmaceutical medicines and medical research. One of the researches is by GW Pharmaceuticals which was reported by The Guardian [5] a couple of weeks ago.

Soporific Effects

One of the primary reasons why many people use marijuana is for its ability to aid in sleep. This property of marijuana manifests due to the presence of THC. CBD, on the other hand, leads to wakefulness and is not ideal for promoting sleep. Strains with high THC often make the user feel sleepy and drowsy as compared to strains with low THC or high CBD.

Legal Status

The legal status of marijuana is pretty black and white – it is illegal in most countries. CBD falls under Schedule I drugs in the U.K. and is thus, illegal, technically speaking. However, CBD Oil which consists of 4% CBD and less than 0.05% THC is legal. Hemp, which consists of CBD is legal and is Legal cannabiseasily sold and bought in a lot of countries, including U.S and the U.K. Thus, derivatives of CBD and THC are easily bought and sold all over the world without any restrictions.

Recently, a lot of research has gone into the benefits of CBD over THC and this is main reason why high CBD cannabis plants are being created by growers. These plants have low THC levels. CBD oil natural supplements are also pretty popular with users.

Source: Cibdol©

 

Cannabinoids are a group of active compounds found in marijuana.

Marijuana contains many chemical compounds that create the different characteristics of the plant. Terpenes provide flavors and aromas, while chlorophyll in the leaves makes the plant green. But the most important chemicals in marijuana are the cannabinoids.

Cannabinoids are the chemicals which give the cannabis plant its medical and recreational properties. Cannabinoids like THC and CBD interact with different receptors in the body to produce a wide range of effects, such as feeling high.

But what exactly are cannabinoids, and why are they able to interact with the body? The answer has to do with cannabinoid receptors in the endocannabinoid system.

Let’s take a deeper look at these fascinating compounds.

Cannabinoids in Marijuana

The marijuana plant produces as many as 113 different cannabinoids. Among these cannabinoids, THC and CBD are the most prevalent and the most well-understood.

Marijuana’s cannabinoids are produced and stored within the trichomes (crystals) of the plant. These trichomes give marijuana flowers their shiny and sparkly appearance.

Most strains of marijuana sold today are cultivated with higher levels of THC. THC is known for its psychoactive properties, and is the reason you feel “high” after ingesting marijuana.

CBD is a non-psychoactive cannabinoid and actually works to counteract the high. CBD also has numerous benefits, such as anti-inflammatory and neuroprotective properties.

While THC and CBD are the most well-known cannabinoids, there are many other cannabinoids in marijuana that offer health benefits. Some of these include cannabigerol (CBG), cannabinol (CBN), and cannabichromene (CBC).

Endocannabinoids

Endocannabinoids are cannabinoids that are produced naturally by the human body. “Endo” stands for endogenous, which means originating within the body.

While these cannabinoids are distinct from those produced in marijuana, they share many similar properties and effects. This is because they interact with the same pathways in the brain and body called cannabinoid receptors.

Scientists believe there are many different endocannabinoids, but the most studied and understood are 2-AG and anandamide.

Other endocannabinoids include noladin ether, virodhamine, and N-arachidonyl dopamine (NADA).

While the functions of these cannabinoids within the body are wide-ranging, it is believed that their primary function is to promote homeostasis.

How Do Cannabinoids Work?

In order to understand cannabinoids, you have to know a bit about the endocannabinoid system. The endocannabinoid system is a system in the human body consisting of cannabinoids and cannabinoid receptors.

These receptors and cannabinoids can be thought of as a lock-and-key system. Cannabinoids bind to cannabinoid receptors like a key fits into a lock. Unlocking the receptor causes changes in how cells function, leading to different effects in the body.

When marijuana enters your body, THC activates the endocannabinoid system by attaching to cannabinoid receptors.

There are two different types of cannabinoid receptors: CB1 and CB2. CB1 receptors are found primarily in the brain, and are responsible for the psychoactive effects of marijuana.

On the other hand, CB2 receptors are found mostly in other parts of the body. They are responsible for a wide range of biological functions.

The functions of the endocannabinoid system help explain the effects of marijuana. The endocannabinoid system is involved with regulating appetite, sleep, pain, mood, memory, and much more.