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For many, taking time out to enjoy oneself sexually, alone or with a partner, can be a difficult task. Often, it’s not through lack of desire, but more a case of brain overload. Many couples and working individuals lead fast-paced, complex lives. Throw in a few social media platforms and the ability for anyone to reach you at a moment’s notice, and suddenly being able to really clear your head and enjoy yourself becomes a tall order. Even if you don’t fall into one of those categories, who doesn’t want more intimate, relaxed sexual experiences?

CBD could be the aid to just that, a more intimate experience with your partner. Or even the chance to just unwind properly before experiencing sexual pleasure. This isn’t about forced scenarios or scheduling out a whole evening to really focus, but much more of a holistic approach. CBD can be naturally and discreetly incorporated into your sex life through a variety of applications. Available in liquid or capsule form, there is a method suitable for all users.

Chemical Link Between Human Orgasm And Cannabis Plant

How can cannabis be linked to the way we feel and the chemical reactions that occur when we orgasm? The answer to that lies in something that is inside all humans, the endocannabinoid system (ECS). This is a complex network of neurochemical pathways located in the brain, central nervous system, and peripheral organs. When these pathways are stimulated by cannabinoids, the key components within cannabis, there can be a variety of positive effects.

It is this manipulation of the endocannabinoid system which has peaked interest in scientists. An experiment published in The Journal Of Sexual Medicine last year looked to investigate endocannabinoid levels in healthy male and female subjects before and after masturbation to orgasm. Endocannabinoids are the cannabinoids naturally produced by our own bodies. Interestingly, scientists found that there was an increase of endocannabinoid 2-AG (2-arachidonoylglycerol) post-orgasm in study participants.

Scientists deduced that the endocannabinoid system did, in fact, play a key part in the human sexual response. The caveat being that more research would be needed to establish what role 2-AG plays when it is released as part of sexual pleasure. Manipulation of this response through cannabinoids could kick-start the process, allowing users to replicate that “reward” chemical reaction.

Cannabinoid Receptors CB1 And CB2

The complexity of the endocannabinoid system comes down to the way it is stimulated. Stimulation is achieved via receptors throughout the system, namely CB1 and CB2. Each receptor is responsible for different chemical reactions and they both respond differently depending on their location in the body. Anandamide and 2-AG are now known to play a part in the “rewarding consequences of sexual arousal and orgasm”, showing us the importance of the endocannabinoid system in facilitating feelings of pleasure.

Relieves Sexual Anxiety And Stress

Understanding the ECS is one thing, but what practical application is there for reducing stress and anxiety? The feeling of being stressed carries with it a number of emotions. Fear, worry, and self-consciousness can all become prevalent when stressed, inhibiting your body’s natural ability to release chemicals like Anandamide and 2-AG. Knowing these play an essential role in experiencing pleasure, it is imperative we try to remove this stress and anxiety to truly feel intimate with our partners and ourselves.

CBD, a phytocannabinoid found in the cannabis plant, takes the limelight in this situation. This cannabinoid is known to relieve stress, yet it carries none of the psychoactive properties associated with THC. For many, sexual experiences while under the influence of a psychoactive substance are not ideal, whereas CBD leaves participants in complete control, but without all the anxiety.

Improves Communication And Vivid Thought

Whilst the ECS plays a part in pleasurable experiences, it is the sexual inhibition system (SIS) and the sexual excitation system (SES) which regulate sexual desire. Successful interaction between these two systems is what many people describe as being “in the mood”, a desire to engage sexually. As the names would indicate, the SIS is designed to inhibit our desire for sex whilst the SES is aimed at encouraging.

Improved communication and intimacy are driven by the strength of our desire. To that end, decreasing the activation of our SIS is essential. Stress actually strengthens the inhibiting abilities of the SIS, preventing the SES from stepping in.

Enhance And Energise

In addition to the aforementioned, several other factors can impact sexual enjoyment. One of those is erectile dysfunction, often a result of weakened blood flow and tissue damage. A potential influence in erectile dysfunction is the build-up of a toxin called dioxin. Promoted by dietary choices and environmental influences, removal of dioxin from the body can only be seen as beneficial. As diverse as we know CBD to be, it can also aid the body in flushing out dioxin, limiting its lingering presence in our fat cells.

CBD has received an enormous amount of attention lately. In fact, it seems not a day goes by without some mention of CBD on social media, the news, or elsewhere.

But what exactly has fueled this interest in CBD? In this article, we explore some of the main reasons CBD has become increasingly popular in recent years.

The Story Of Charlotte’s Web

Undoubtedly, one of the most influential catalysts leading to CBD’s rise in popularity was the release of a 2013 news report on “Charlotte’s Web.”

Charlotte’s Web is a potent CBD extract manufactured by the Stanley Brothers from Colorado, USA. It is named after Charlotte Figi, a young girl from Boulder, Colorado, who uses the oil for severe epileptic seizures.

Charlotte’s story first made headlines in 2013, after CNN published an in-depth report exploring the ameliorative potential of CBD, especially for seizures and tremors caused by severe forms of epilepsy like Dravet Syndrome.

This report shined a global spotlight not only on Charlotte and other children like her, but also on CBD specifically. Since its broadcast in 2013, countless other reports have further explored CBD, it’s chemical makeup, effects on the body, and therapeutic potential.

Increased Research

Another major factor influencing the rise of CBD is an increase in scientific research of cannabis and hemp plants.

While humans have used cannabis for thousands of years, it is only in the last few years that we’ve really begun understanding the plant, its many compounds, and the effects they can have on the human body.

For example, THC (the main psychoactive ingredient in cannabis) was only isolated from the plant in 1964 (just over 50 years ago); human cannabinoid receptors and endogenous cannabinoids (like anandamide and 2-AG) were only discovered in the late 1980s and early 1990s.

Ever since, a growing body of research has tried to better understand cannabis. This research has not only helped the general populace better understand the cannabis plant, it has built up a lot of awareness about specific compounds, such as CBD.

Legality And Accessibility

Legality is a big topic in the cannabis industry. “Legalize cannabis” campaigns have gained a lot of momentum across the world, which is another major reason CBD and other cannabinoids have become more widespread.

This is mainly because CBD, unlike THC, is less restricted in many countries. This is largely due to the fact that CBD is a non-psychoactive cannabinoid, meaning it doesn’t interfere with normal physical or psychological functioning.

In the US, for example, CBD products with less than 1% THC are completely legal and can be purchased online and shipped virtually all around the country.

The same is true in many European countries. In Switzerland, for example, products like hemp cigarettes containing 4mg of CBD can be purchased like regular cigarettes and tobacco products at supermarkets and kiosks.

The fact that CBD is less restricted than THC and other cannabinoids makes it much more appealing for consumers looking to use cannabis and hemp products. It also makes it much easier to ship and market these products, making them more accessible.

Increased Market Size

Another contributing factor to CBD’s boom is increased market size.

The cannabis industry, in general, is already experiencing massive growth. In the US, for example, it is estimated to be worth over USD $20 billion by 2020. But the demand for CBD products is especially high. The market for CBD-rich hemp and hemp-derived products is already valued at roughly USD $130 million according to a 2016 market estimate by Vote Hemp and the Hemp Business Journal.

The United States is seeing a big increase in CBD companies, offering everything from food supplements (like hemp seed), to products like CBD-rich tinctures, to cosmetics, body creams, lotions, and more.

In Europe, the demand for CBD is pegged at roughly €2 billion, according to research by nova-Institute and HempConsult, two German companies who researched the European market potential for non-psychoactive CBD products.

This growing market size directly stimulates the popularity of CBD. With more companies and products on the market, customers are being presented with more information about CBD and its many potential uses.

Increased Awareness

All of the factors we’ve discussed in this article so far (increased research, improved accessibility, and bigger market size) are significant on their own. However, together they work to generally increase awareness of CBD on a global scale.

The research into CBD, for example, is fueling countless media reports on new scientific studies exploring every aspect of this unique chemical.

Meanwhile, the fact that CBD is accessible and legal makes it easier for consumers to experiment with CBD products and try them out for themselves. The growing market potential also means that companies and other interested groups are putting together more information about CBD and making it regularly available.

And in today’s day and age, it’s easier than ever before to disseminate that information and reach a global audience. Through increased media attention and the rise of social media, people are coming into contact with CBD-related information on a daily basis, regardless of where they live.

CBD Is Extremely Versatile

Last, but not least, one of the main reasons CBD has become so popular is because of its versatility.

For some, it’s an important nutritional supplement; for others, a new addition to their health and beauty routine.

To find out more about CBD and how it can help you improve different aspects of your life, check out our website and place your order today.

Source: Cibdol©

Researchers are working on cannabinoids to target both diabetes causes and symptoms. The maintenance of a stable homeostatic environment in our body seems to be the key for novel cannabis treatment against diabetes. A cure is yet to come, but some symptoms may be mitigated with cannabis flowers and extracts.

Diabetes is a set of metabolic diseases derived by the body’s inability in regulating the amount of sugars, particularly glucose, in blood. Glucose levels are regulated by hormones such as insulin, produced in the pancreas. Diabetes can cause long-term complications like cardiovascular disease, stroke, damages to kidneys and eyes.

The cannabinoid system is involved in the bloodsuger affair

A growing body of research is confirming the anecdotal evidence built among diabetes patients, showing that cannabis can have beneficial effects. THC and CBD anti-inflammatory action may help with the arterial inflammation, which is common in diabetes, while the neuroprotective effect can reduce inflammation of nerves and related pain. Cannabinoids can also act as vasodilators, improving blood circulation and exerting an anti-spasmodic action on muscle cramps and gastrointestinal disorders. The typical diabetic restless syndrome might also be addressed with cannabis to help patients sleep better. Recent lab studies are also showing that the endocannabinoid system could actually be targeted to stabilize the blood sugar level, thus pointing at the core of the disease. Unfortunately that’s lab research. There isn’t any cannabis therapy today conceivable against diabetes.

Diabetic mice get better with cannabis in laboratories

Though lacking clinical research on human patients, lab experiments demonstrate a strict correlation between diabetes’ activity and cannabinoids. One of the first studies evidencing the influence of the endocannabinoid system on diabetes was published in 2006 with the title “Cannabidiol lowers incidence of diabetes in non-obese diabetic mice”. This study was indicating that CBD can inhibit and delay destructive insulitis and inflammatory cytokine production, resulting in a decreased incidence of diabetes.

Researchers also wrote about a possible specific immunomodulatory mechanism activated by CBD. That hypothesis is confirmed by other findings about cannabidiol, arresting the onset of autoimmune diabetes in mice, and by one study that discovered some neuroprotective effects of CBD in an experimental model of diabetes. A research also finds that CBD attenuates cardiac dysfunction in diabetic cardiomyopatic mice.

A study titled “Marijuana in the Management of Diabetes” was published in the American Journal of Medicine in 2013. In this report, past and current cannabis use was associated with lower levels of fasting insulin, blood glucose, and insulin resistance. According to this study, cannabis users are less likely to become obese, and have lower body mass index measurements. Cannabis smokers also had higher levels of “good cholesterol” and smaller waist circumference. An important finding of this research is that cannabis users appeared to have better carbohydrate metabolism than non-users, which is kind of confirming the lab test results we have seen before.

One of the latest important studies dates back in 2015, when scientists led by Raphael Mechoulam, well known for discovering CBD, showed that the anti-inflammatory properties of cannabidiol could be used to treat different illnesses, including type 2 diabetes. Finally, **an October 2016 research showed that an experimental CBD treatment reduced the markers of inflammation in the microcirculation of the pancreas in mice. All these studies conclude that cannabis compounds have a role in controlling blood sugar levels and in mitigating pain or other symptoms of diabetes. We still don’t know how to make a medicine from these findings.

A study from October 2016

Mitigating thesymptoms of diabetes with CBD

Out of the labs and into patients’ houses, there is a whole body of evidence showing that cannabis is effective in treating eye disorders, chronic pain, sleep disorders, and other ailments associated with diabetes. The way people are treated for diabetes also depends on whether or not the person has additional complications, and their general health. Some patients are complementing their therapies with cannabinoids.

Cannabis may initially promote appetite and overeating, yet in the long run it has the opposite effect, and may even protect against obesity. Cannabis extracts with different proportions between THC, CBD, other cannabinoids and terpenes, or just containing the non-psychotropic CBD can benefit cardiac and arterial health. The same hemp or cannabis extracts can be used to make topical creams to relieve neuropathic pain. Conversely, a possible risk of cannabis use with diabetes is hypoglycaemia, as there are some concerns that glucose levels might drop unnoticed by the patient until they are in dangerous territory.

Any form of exercise on a regular basis, together with a healthy, well-balanced diet can reduce the risk of developing diabetes and control blood sugar levels in persons with this disease. Diabetes patients should also moderate or quit smoking and drinking alcohol.

Source: Cibdol©

CBD stands for Cannabidiol and THC stands for tetrahydrocannabidiol. They are both key ingredients in marijuana plants. Cannabinoids are a unique class of compounds and both CBD and THC belong to this class. High THC strains are common when it comes to marijuana but strains with high CBD are rare. The following are a few key differences found between CBD and THC.

What is CBD?

Cannabis has more than 60 cannabinoids and CBD [1] is one of them. It is usually marketed in chewable, cream and liquid forms on its own. It interacts with the receptor cells and boosts the response of the nervous system in the human body. Human body has two cannabinoid receptors – CB-1 and CB-2. It is also a natural suppressant.

What is THC?

THC [2] is not only one of the 60 cannabinoids but it is also the major psychoactive ingredient found in cannabis. THC happens to be the most researched and popularly recognized compounds of cannabis. It interlocks with the nerve cell receptors but the reaction is quite different from that of drugs like morphine and heroin. Dopamine is released as a result of THC’s interaction with the brain. The effects of THC last for 2 hours. The effects start within 10 – 30 minutes of ingestion.

High

Marijuana’s most psychoactive ingredient is probably THC but CBD, on the other hand, is completely non-psychoactive. This is why THC gives users a high effect while CBD does not. This is why recreational users never prefer CBD but its non-psychoactive properties have made it a good candidate for medical research.

Anxiety and Paranoia Related Side Effects

Paranoia and anxiety are some side-effects of using THC which many users have experienced. On the other hand, CBD has fared better in this area. A scientific paper [3] studied the psychotomimetic effects of both CBD and THC in 134 users and CBD showed no results related to causing paranoia and anxiety.

Antipsychotic

THC has effects similar to psychosis. On the other hand, CBD is non-psychoactive and also helps to counteract the psychoactive effects of THC. A research paper [4] showed that CBD had properties to reduce the high of users because of its antipsychotic capability. CBD as one of the active compounds in various pharmaceutical medicines and medical research. One of the researches is by GW Pharmaceuticals which was reported by The Guardian [5] a couple of weeks ago.

Soporific Effects

One of the primary reasons why many people use marijuana is for its ability to aid in sleep. This property of marijuana manifests due to the presence of THC. CBD, on the other hand, leads to wakefulness and is not ideal for promoting sleep. Strains with high THC often make the user feel sleepy and drowsy as compared to strains with low THC or high CBD.

Legal Status

The legal status of marijuana is pretty black and white – it is illegal in most countries. CBD falls under Schedule I drugs in the U.K. and is thus, illegal, technically speaking. However, CBD Oil which consists of 4% CBD and less than 0.05% THC is legal. Hemp, which consists of CBD is legal and is Legal cannabiseasily sold and bought in a lot of countries, including U.S and the U.K. Thus, derivatives of CBD and THC are easily bought and sold all over the world without any restrictions.

Recently, a lot of research has gone into the benefits of CBD over THC and this is main reason why high CBD cannabis plants are being created by growers. These plants have low THC levels. CBD oil natural supplements are also pretty popular with users.

Source: Cibdol©

CBD, or cannabidiol, is one of the main compounds found in hemp and cannabis plants. It has received a lot of attention recently for its wide array of beneficial properties.

But how exactly does CBD work? Unfortunately, the answer to this question is very complex. CBD impacts receptors all over the body, producing a variety of outcomes, including those affecting hormone production.

In this article, we explore how CBD affects the endocrine system and the production of hormones like cortisol, insulin, and melatonin.

UNDERSTANDING HORMONES AND THE ENDOCRINE SYSTEM

Before we look at the specific effects of CBD on hormones, it’s important to have a basic understanding of hormones themselves, the endocrine system, and the relationship between the two.

Hormones are essentially chemical messengers. They are involved in numerous bodily processes, including growth and development, metabolism and appetite, sexual function, reproduction, and mood.

The endocrine system is made up of a variety of glands that produce hormones, such as the thyroid, pancreas, pineal gland, and others. The hormones produced by these glands are particularly powerful chemicals that can sustain major effects on the body, even in small amounts.

HOW CBD AFFECTS HORMONES

When we ingest cannabinoids like CBD, they interact with our body’s natural endocannabinoid system, or ECS. This is a complex system involved in managing bodily processes, including appetite, mood, and many more.

Studies have shown that the endocannabinoid system is also involved in managing endocrine processes. It does so by activating receptors in the brain and body, which directly influence activity in endocrine glands like the thyroid, pineal, and pituitary glands.

Hence, by stimulating the endocannabinoid system, CBD and other cannabinoids can directly affect hormone levels in the body. Below are examples of how CBD affects the levels of major hormones.

CBD AND CORTISOL

One of the major roles of the endocrine system is to manage our response to stress. It does so via hormones like epinephrine (also known as adrenaline) and cortisol.

Cortisol is one of the main hormones involved in managing stress response. It is also involved in managing metabolism, memory, and even the healing of wounds. The human body naturally produces cortisol in the adrenal gland.

Cortisol is vital to human survival and is responsible for mediating our natural “fight or flight” response. However, increased levels of cortisol are problematic, producing symptoms that can range from weight gain and mood swings to increased anxiety.

Numerous studies have already argued that CBD can directly affect hormone levels. More specifically, studies have found that CBD lowers cortisol levels in the brain by interfering with the excretion of the hormone in the adrenal gland. This is extremely important in managing the balance of healthy cortisol levels and reducing symptoms of stress.

CBD AND INSULIN

Another important role of the endocrine system is managing metabolism. One of the many ways it does so is by producing vital hormones in the pancreas. These hormones include glucagon, somatostatin, and insulin, among others.

Insulin is an important hormone that helps the body absorb and store nutrients from food. Without insulin, sugar from food would not be able to pass from your bloodstream into individual cells.

Much like with cortisol (and most other hormones), insulin imbalances can have detrimental effects on one’s health. A lack of insulin, for example, leads to an increase in blood sugar levels (hyperglycemia), while too much insulin leads to low blood sugar (hypoglycemia).

One of the most common conditions arising from insulin problems is diabetes. People with diabetes suffer from constantly high blood sugar levels because their bodies struggle to produce or use insulin properly.

A wide variety of studies have explored the effects of cannabinoids on metabolism, as well as the relationship between cannabinoids and diabetes. Some studies have shown that CBD can directly impact the functioning of the pancreas, ultimately affecting insulin production, blood sugar levels, and more.

CBD AND MELATONIN

It goes without saying that sleep is extremely important for good health. Our endocrine system is heavily involved in managing sleep by using hormones like melatonin to induce sleep or manage energy levels. Melatonin is produced in the pineal gland of the brain.

Melatonin is one of the most important hormones involved in our sleep cycle. For example, melatonin levels change based on our circadian rhythm and tend to spike in the evening. Environmental factors such as darkness also impact melatonin levels.

The endocannabinoid system has been shown to be very involved in the management of sleep. In fact, a study published in the Public Library Of Science’s journal PLoS One found that the endocannabinoid system directly regulates sleep stability via activation of CB1 receptors.

Cannabinoid receptors have been found in many different glands of the endocrine system. By activating receptors in the pineal gland, CBD may help stimulate the secretion of sleep hormones like melatonin, ultimately affecting sleep and energy levels.

CBD AND HOMEOSTASIS

Studies have shown that cannabinoids like CBD can have direct influences on the production and secretion of hormones like cortisol, insulin, melatonin, and others. Therefore, cannabinoids and the endocannabinoid system sustain a direct influence on homeostasis.

Homeostasis refers to the internal balance needed for organisms to function properly. In humans, homeostasis basically ensures we are in working order. Some examples of the variables that maintain this balance include:

• Body temperature
• Appetite
• Thirst
• Heart rate
• Blood pressure
• Sleep cycle

One of the key areas responsible for regulating these variables is the hypothalamus, a region of the brain made up of nerve cell clusters located just above the brainstem. The hypothalamus is one of the main parts of the body’s endocrine system.

Just like other regions of the brain, the hypothalamus contains cannabinoid receptors. Research suggests that targeting these receptors and stimulating them with cannabinoids like CBD, for example, can help manage the many processes required for homeostasis.

SUPPLEMENTING WITH CBD

As we’ve seen, CBD and the endocannabinoid system have very clear effects on hormone levels in the body. If you suffer from hormonal imbalances, CBD may help you bring homeostasis back to your body.

To find out more about CBD, click here. For more information about products and to place your order, visit our webstore today!

Source: Cibdol©

CBD Oil is Catching the Attention of Veterinarians

Applying cannabis as a supplement for dogs, cats, and other furry friends is very much like it is with humans: not everybody is in agreement or on the same page.

CBD hemp oil (which contains virtually no THC) as a daily nutritional supplement still faces stigma and scrutiny from human doctors and veterinarians alike. This can be attributed to a handful of reasons, ranging from lack of research to a head-in-the-sand mindset regarding anything to do with marijuana.

However, just like human M.D.s, there are also several animal doctors and vets who not only accept CBD oil as a treatment for pets, they swear by it and often recommend it. Some pet owners aren’t waiting for the science or the law to catch up with what they see as a viable option for treating their pets’ illnesses or making them more comfortable.

In this entry, we’ll hear why some vets and pet owners support CBD for pets, and then you can make the decision about whether your animal friend could benefit from a daily serving of CBD.

Veterinary Medicine And Cannabis
Humans have used cannabis for quite some time. Some archeological sites have been discovered to show that cannabis was in use—even cultivated—for at least 10,000 years. Point being, even though CBD hemp oil is a relatively new addition to the cannabis world, hemp and humans have had a long and fruitful history.

Every day, more research and anecdotal evidence emerges about the benefits of taking a daily serving of CBD oil. Humans and mammals share the same type of homeostatic system within their bodies (more on that in just a bit), so naturally some forward-thinking vets believe that animals, including your Fido and kitty cat, can also benefit from CBD. You may be unfamiliar with what CBD oil is and how it works, so let’s do a quick review to get you up to speed.

What Is CBD Oil?
CBD oil is extracted from the stalks and seeds of hemp plants. CBD is short for Cannabidiol. It is one of over 85 cannabinoids presently found in the cannabis plant and is the second most abundant cannabinoid in marijuana after THC. In hemp, however, THC is only present in trace amounts. In other words, CBD oil will not get you high.

How CBD Interacts With Mammals
CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. As our environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to help keep us level.

The endocannabinoid system is found in all mammals, and is made up of millions of cannabinoid receptor sites located primarily throughout the brain and central nervous system (CB1 receptors) and immune system (CB2 receptors) that act in neural communication.

It’s clear that the endocannabinoid system is one of the most important regulatory systems in the human body, but most people do very little to support the health of this system, because cannabinoids have not been part of the average diet. This same line of thinking also applies to your pet’s body!

What Aare The Benefits Of CBD Oil For Pets?
Although the AVMA (American Veterinary Medical Association) has no official stance or approval concerning CBD oil as a nutritional supplement, many vets and pets owners are convinced that CBD oil can be taken for as a supplement to help many conditions their animals experience.

The cannabinoid CBD interacts with the receptors in the body and can help modulate things like nausea, general health, and much more. There are also no life-threatening side effects with proper serving usage, and no damage to the kidney, liver, or GI tract.

As with any medication, pet owners should consult their veterinarian first before treating their dog with CBD oil. You may need to seek out a veterinarian who has experience with pets being treated with cannabis oil to discuss proper serving size and reputable manufacturers.

Note: Although CBD hemp oil is beneficial to health, CBDedication.com does not make any medical claims based on the products we sell and should not be used with the intention of curing, or improving an illness.

With cannabidiol (CBD) in the media as much as it is these days, you may be asking; Why should I use CBD oil?

There are many benefits to taking CBD products, but the most exciting among them is that a CBD oil supplement helps augment the body’s naturally occurring endocannabinoids, increasing the body’s ability to promote homeostasis within its systems.

Cannabinoids are a class of active chemical compounds produced by the cannabis plant. These cannabinoids act on cannabinoid receptors located in our cells as part of the endocannabinoid system and alter the release of neurotransmitters in the brain. The endocannabinoid system predominantly consists of two endocannabinoid receptors: CB1, located in the central nervous system, and CB2, found throughout the peripheral nervous system.

There are over 100 presently discovered cannabinoids, which are largely responsible for the effects cannabis has on the body. Common cannabinoids include tetrahydrocannabinol (THC), cannabidiol (CBD), cannabinol (CBN), and cannabigerol (CBG). Cannabinoids work together with the body’s endocannabinoid system to regulate the body’s natural functions – including mood, sleep, appetite, and immune response.

Once the endocannabinoid system is supplemented in this way, it is able to function more efficiently, optimizing the body’s performance each day. Although it is not critical to supplement the endocannabinoid system daily, doing so may increase the effectiveness of CBD and the endocannabinoid system.

Because CBD oil products are categorized as supplements, we comply with the FDA’s DSHEA guidelines and cannot endorse any specific medical benefits of CBD or hemp oil. To further comply with FDA regulations, CBDedication.com does not list any Recommended Daily Intake (RDI) of our own, nor do we provide a Daily Value (%DV) for any of the products we sell. We encourage you to browse the thousands of reputable studies regarding CBD published online and talk with your doctor to see if a CBD supplement is right for you.

Note: Because each individual is unique, it’s  important to do research and speak with a physician or doctor regarding health-related questions or concerns that are specific to patient history. Although CBD hemp oil is beneficial to health, CBDedication.com does not make any medical claims based on the products we sell and should not be used with the intention of curing, or improving an illness.