Shopping for CBD oil can be a challenge. Since there are so many products available in today’s cannabidiol market, it’s important to know what characteristics to look out for, especially if you want the highest quality oil that money can buy. Just because companies label their products as “safe” and “all-natural” doesn’t mean that’s what you’re going to get. How the oil is made and what ingredients are contained within is how you know for sure that you’re getting a product that will actually benefit you, not harm you. This article will inform you of precisely what attributes every CBD oil should have, so that you can soon begin enjoying all the incredible benefits that this groundbreaking cannabinoid has to offer.

TERPENES

Terpenes are hydrocarbons released by the same glands (trichomes) as THC and CBD. Although they don’t produce any psychoactive effects, they do boost the therapeutic potential of CBD oil. Terpenes are also responsible for giving the oil its pungent aroma and satisfying taste. In addition to fighting off unwanted pests during the flowering period, while at the same time attracting pollinators, the combination of piney, earthy, and lemony flavours of terpenes provide the consumer with a delightful CBD experience.

CO₂ EXTRACT

One thing you don’t want when it comes to CBD oil is a product loaded with synthetic chemicals; these toxic additives prevent the cannabinoids from doing their job. If you want the cleanest oil possible, you’re going to want a product that’s made using CO₂ extractions. The difference between CO₂ and butane extractions, for example, is that butane extracts aren’t designed for human consumption. Not to mention, they give off quite an unpleasant taste and can leave toxic residue behind. With CO₂ extracts, the flavour will be a lot purer and more comfortable to ingest compared to other solvents.

DECARBOXYLATED

CBD oil may seem all the same. But in reality, not all products are created equal. Decarboxylation is the process of removing the carboxyl group by applying heat to hemp flowers over an extended period of time. As a result, the inactive compound CBDA is activated and then able to provide a broad range of potential benefits. When CBD oil is not decarboxylated, the product is often cheaper, and at the same time, less efficient. While it may seem like an attractive option when you’re on a tight budget, you actually just wind up wasting your money when you decide to go with a cheaper product rather than one that is a bit more expensive. Nine times out of ten, it’s the higher-priced product that’s going to provide peak levels of CBD.

NATURAL INGREDIENTS

Everyone wants to get their hands on CBD oil. Because it’s in such high demand, companies often try to speed up the production process with high-yield extractions. During this process, manufacturers will use synthetic fertilisers, pesticides, and herbicides. Although they all encourage growth, they also eliminate the therapeutic effects. These methods also destroy several of the present terpenes and flavonoids, which can result in unexpected outcomes after consumption. Choosing a product that consists of a rich phytocomplex of ingredients is paramount when selecting the safest, cleanest, and most effective products.

TEST REPORTS

Companies can promise quality CBD oil all day long. But if it hasn’t undergone the proper testing, there’s no way for the consumer to know if what they’re ingesting is actually safe or not. Always be on the lookout for test reports. Both on-site and third party tests are crucial to ensuring quality. Manufacturers that take the time to confirm the materials they’re using are free of bacteria, harmful contaminants, and artificial additives are more likely to provide you with accurate information on their bottles, and a better product to boot.

NO CBD CRYSTALS

CBD crystals, in particular, contain near-pure concentrations of CBD. However, they lack the therapeutic qualities that draw people to CBD oil in the first place. These supplements don’t offer any of the other terpenes and cannabinoids that make CBD oils broadly effective. Whole plant oils, on the other hand, retain the entire cannabinoid and terpene spectrum of the cannabis plant (except for psychoactive THC), allowing all the naturally-occurring compounds to work together in synergy. This theory is known as the “entourage effect”, which argues that a diverse internal plant environment is key to the efficacy of CBD and other hemp-derived products.

Source: Cibdol©

Researchers are working on cannabinoids to target both diabetes causes and symptoms. The maintenance of a stable homeostatic environment in our body seems to be the key for novel cannabis treatment against diabetes. A cure is yet to come, but some symptoms may be mitigated with cannabis flowers and extracts.

Diabetes is a set of metabolic diseases derived by the body’s inability in regulating the amount of sugars, particularly glucose, in blood. Glucose levels are regulated by hormones such as insulin, produced in the pancreas. Diabetes can cause long-term complications like cardiovascular disease, stroke, damages to kidneys and eyes.

The cannabinoid system is involved in the bloodsuger affair

A growing body of research is confirming the anecdotal evidence built among diabetes patients, showing that cannabis can have beneficial effects. THC and CBD anti-inflammatory action may help with the arterial inflammation, which is common in diabetes, while the neuroprotective effect can reduce inflammation of nerves and related pain. Cannabinoids can also act as vasodilators, improving blood circulation and exerting an anti-spasmodic action on muscle cramps and gastrointestinal disorders. The typical diabetic restless syndrome might also be addressed with cannabis to help patients sleep better. Recent lab studies are also showing that the endocannabinoid system could actually be targeted to stabilize the blood sugar level, thus pointing at the core of the disease. Unfortunately that’s lab research. There isn’t any cannabis therapy today conceivable against diabetes.

Diabetic mice get better with cannabis in laboratories

Though lacking clinical research on human patients, lab experiments demonstrate a strict correlation between diabetes’ activity and cannabinoids. One of the first studies evidencing the influence of the endocannabinoid system on diabetes was published in 2006 with the title “Cannabidiol lowers incidence of diabetes in non-obese diabetic mice”. This study was indicating that CBD can inhibit and delay destructive insulitis and inflammatory cytokine production, resulting in a decreased incidence of diabetes.

Researchers also wrote about a possible specific immunomodulatory mechanism activated by CBD. That hypothesis is confirmed by other findings about cannabidiol, arresting the onset of autoimmune diabetes in mice, and by one study that discovered some neuroprotective effects of CBD in an experimental model of diabetes. A research also finds that CBD attenuates cardiac dysfunction in diabetic cardiomyopatic mice.

A study titled “Marijuana in the Management of Diabetes” was published in the American Journal of Medicine in 2013. In this report, past and current cannabis use was associated with lower levels of fasting insulin, blood glucose, and insulin resistance. According to this study, cannabis users are less likely to become obese, and have lower body mass index measurements. Cannabis smokers also had higher levels of “good cholesterol” and smaller waist circumference. An important finding of this research is that cannabis users appeared to have better carbohydrate metabolism than non-users, which is kind of confirming the lab test results we have seen before.

One of the latest important studies dates back in 2015, when scientists led by Raphael Mechoulam, well known for discovering CBD, showed that the anti-inflammatory properties of cannabidiol could be used to treat different illnesses, including type 2 diabetes. Finally, **an October 2016 research showed that an experimental CBD treatment reduced the markers of inflammation in the microcirculation of the pancreas in mice. All these studies conclude that cannabis compounds have a role in controlling blood sugar levels and in mitigating pain or other symptoms of diabetes. We still don’t know how to make a medicine from these findings.

A study from October 2016

Mitigating thesymptoms of diabetes with CBD

Out of the labs and into patients’ houses, there is a whole body of evidence showing that cannabis is effective in treating eye disorders, chronic pain, sleep disorders, and other ailments associated with diabetes. The way people are treated for diabetes also depends on whether or not the person has additional complications, and their general health. Some patients are complementing their therapies with cannabinoids.

Cannabis may initially promote appetite and overeating, yet in the long run it has the opposite effect, and may even protect against obesity. Cannabis extracts with different proportions between THC, CBD, other cannabinoids and terpenes, or just containing the non-psychotropic CBD can benefit cardiac and arterial health. The same hemp or cannabis extracts can be used to make topical creams to relieve neuropathic pain. Conversely, a possible risk of cannabis use with diabetes is hypoglycaemia, as there are some concerns that glucose levels might drop unnoticed by the patient until they are in dangerous territory.

Any form of exercise on a regular basis, together with a healthy, well-balanced diet can reduce the risk of developing diabetes and control blood sugar levels in persons with this disease. Diabetes patients should also moderate or quit smoking and drinking alcohol.

Source: Cibdol©

CBD, or cannabidiol, is one of the main compounds found in hemp and cannabis plants. It has received a lot of attention recently for its wide array of beneficial properties.

But how exactly does CBD work? Unfortunately, the answer to this question is very complex. CBD impacts receptors all over the body, producing a variety of outcomes, including those affecting hormone production.

In this article, we explore how CBD affects the endocrine system and the production of hormones like cortisol, insulin, and melatonin.

UNDERSTANDING HORMONES AND THE ENDOCRINE SYSTEM

Before we look at the specific effects of CBD on hormones, it’s important to have a basic understanding of hormones themselves, the endocrine system, and the relationship between the two.

Hormones are essentially chemical messengers. They are involved in numerous bodily processes, including growth and development, metabolism and appetite, sexual function, reproduction, and mood.

The endocrine system is made up of a variety of glands that produce hormones, such as the thyroid, pancreas, pineal gland, and others. The hormones produced by these glands are particularly powerful chemicals that can sustain major effects on the body, even in small amounts.

HOW CBD AFFECTS HORMONES

When we ingest cannabinoids like CBD, they interact with our body’s natural endocannabinoid system, or ECS. This is a complex system involved in managing bodily processes, including appetite, mood, and many more.

Studies have shown that the endocannabinoid system is also involved in managing endocrine processes. It does so by activating receptors in the brain and body, which directly influence activity in endocrine glands like the thyroid, pineal, and pituitary glands.

Hence, by stimulating the endocannabinoid system, CBD and other cannabinoids can directly affect hormone levels in the body. Below are examples of how CBD affects the levels of major hormones.

CBD AND CORTISOL

One of the major roles of the endocrine system is to manage our response to stress. It does so via hormones like epinephrine (also known as adrenaline) and cortisol.

Cortisol is one of the main hormones involved in managing stress response. It is also involved in managing metabolism, memory, and even the healing of wounds. The human body naturally produces cortisol in the adrenal gland.

Cortisol is vital to human survival and is responsible for mediating our natural “fight or flight” response. However, increased levels of cortisol are problematic, producing symptoms that can range from weight gain and mood swings to increased anxiety.

Numerous studies have already argued that CBD can directly affect hormone levels. More specifically, studies have found that CBD lowers cortisol levels in the brain by interfering with the excretion of the hormone in the adrenal gland. This is extremely important in managing the balance of healthy cortisol levels and reducing symptoms of stress.

CBD AND INSULIN

Another important role of the endocrine system is managing metabolism. One of the many ways it does so is by producing vital hormones in the pancreas. These hormones include glucagon, somatostatin, and insulin, among others.

Insulin is an important hormone that helps the body absorb and store nutrients from food. Without insulin, sugar from food would not be able to pass from your bloodstream into individual cells.

Much like with cortisol (and most other hormones), insulin imbalances can have detrimental effects on one’s health. A lack of insulin, for example, leads to an increase in blood sugar levels (hyperglycemia), while too much insulin leads to low blood sugar (hypoglycemia).

One of the most common conditions arising from insulin problems is diabetes. People with diabetes suffer from constantly high blood sugar levels because their bodies struggle to produce or use insulin properly.

A wide variety of studies have explored the effects of cannabinoids on metabolism, as well as the relationship between cannabinoids and diabetes. Some studies have shown that CBD can directly impact the functioning of the pancreas, ultimately affecting insulin production, blood sugar levels, and more.

CBD AND MELATONIN

It goes without saying that sleep is extremely important for good health. Our endocrine system is heavily involved in managing sleep by using hormones like melatonin to induce sleep or manage energy levels. Melatonin is produced in the pineal gland of the brain.

Melatonin is one of the most important hormones involved in our sleep cycle. For example, melatonin levels change based on our circadian rhythm and tend to spike in the evening. Environmental factors such as darkness also impact melatonin levels.

The endocannabinoid system has been shown to be very involved in the management of sleep. In fact, a study published in the Public Library Of Science’s journal PLoS One found that the endocannabinoid system directly regulates sleep stability via activation of CB1 receptors.

Cannabinoid receptors have been found in many different glands of the endocrine system. By activating receptors in the pineal gland, CBD may help stimulate the secretion of sleep hormones like melatonin, ultimately affecting sleep and energy levels.

CBD AND HOMEOSTASIS

Studies have shown that cannabinoids like CBD can have direct influences on the production and secretion of hormones like cortisol, insulin, melatonin, and others. Therefore, cannabinoids and the endocannabinoid system sustain a direct influence on homeostasis.

Homeostasis refers to the internal balance needed for organisms to function properly. In humans, homeostasis basically ensures we are in working order. Some examples of the variables that maintain this balance include:

• Body temperature
• Appetite
• Thirst
• Heart rate
• Blood pressure
• Sleep cycle

One of the key areas responsible for regulating these variables is the hypothalamus, a region of the brain made up of nerve cell clusters located just above the brainstem. The hypothalamus is one of the main parts of the body’s endocrine system.

Just like other regions of the brain, the hypothalamus contains cannabinoid receptors. Research suggests that targeting these receptors and stimulating them with cannabinoids like CBD, for example, can help manage the many processes required for homeostasis.

SUPPLEMENTING WITH CBD

As we’ve seen, CBD and the endocannabinoid system have very clear effects on hormone levels in the body. If you suffer from hormonal imbalances, CBD may help you bring homeostasis back to your body.

To find out more about CBD, click here. For more information about products and to place your order, visit our webstore today!

Source: Cibdol©

Sleeping problems are common. According to multiple surveys, more than 50% experience sleeping problems.

We do not have to explain that sleep problems are annoying. And certainly not to the people who experience this themselves. A disturbed night’s sleep has adverse health effects. A good night’s sleep not only provides a fit body and a fresh head, but is also important for the immune system.

Your body recovers itself from the day during sleep. A good night’s sleep will make your immune system stronger and more resistant to diseases and disorders such as tension and stress. This is particularly important in the long term; a sleep problem does not always have noticeable consequences in the short term, but after a longer period of time it can facilitate and even strengthen the development of disorders.

Melatonin

Our body promotes sleep, among other things, with the Melatonin substance. Melatonin is a hormone that is produced in the pineal gland in the brain. This substance ensures that the body becomes tired and sleepy.

Melatonin is normally only produced when the daylight decreases. During the day only small concentrations of this substance are present in the body, but in the evening and night the concentration of this substance increases. Due to, among other things, stress and stress, the production of Melatonin can be seriously disrupted, resulting in a poor night’s sleep.

Fighting Sleeping Problems

Many means and medicines are available for sleep problems. Often these contain chemical components, but nowadays there are fortunately also completely natural products available.

CBD naturally has a calming and sleep-promoting effect. Various studies have shown that CBD stimulates a normal sleep pattern.

A new and revolutionary product in this area is Meladol from the Swiss manufacturer Cibdol. In addition to the active ingredient CBD, Meladol also contains the body’s own substance Melatonin and vitamin B6.

Meladol can be a good way for many people to combat their sleep problems. The soothing effect of CBD in combination with the sleep-promoting effect of Melatonin, makes Meladol a night-rest stimulating powerhouse.

It is very easy to use: 1 x 1 ml 15 minutes before bedtime with the help of the clearly readable pipette. Drip it directly in the mouth or in a glass of water or juice and swallow it directly. Do not take more than the recommended amount. A bottle contains 30ml and is therefore sufficient for a whole month.

 

CBD Oil is Catching the Attention of Veterinarians

Applying cannabis as a supplement for dogs, cats, and other furry friends is very much like it is with humans: not everybody is in agreement or on the same page.

CBD hemp oil (which contains virtually no THC) as a daily nutritional supplement still faces stigma and scrutiny from human doctors and veterinarians alike. This can be attributed to a handful of reasons, ranging from lack of research to a head-in-the-sand mindset regarding anything to do with marijuana.

However, just like human M.D.s, there are also several animal doctors and vets who not only accept CBD oil as a treatment for pets, they swear by it and often recommend it. Some pet owners aren’t waiting for the science or the law to catch up with what they see as a viable option for treating their pets’ illnesses or making them more comfortable.

In this entry, we’ll hear why some vets and pet owners support CBD for pets, and then you can make the decision about whether your animal friend could benefit from a daily serving of CBD.

Veterinary Medicine And Cannabis
Humans have used cannabis for quite some time. Some archeological sites have been discovered to show that cannabis was in use—even cultivated—for at least 10,000 years. Point being, even though CBD hemp oil is a relatively new addition to the cannabis world, hemp and humans have had a long and fruitful history.

Every day, more research and anecdotal evidence emerges about the benefits of taking a daily serving of CBD oil. Humans and mammals share the same type of homeostatic system within their bodies (more on that in just a bit), so naturally some forward-thinking vets believe that animals, including your Fido and kitty cat, can also benefit from CBD. You may be unfamiliar with what CBD oil is and how it works, so let’s do a quick review to get you up to speed.

What Is CBD Oil?
CBD oil is extracted from the stalks and seeds of hemp plants. CBD is short for Cannabidiol. It is one of over 85 cannabinoids presently found in the cannabis plant and is the second most abundant cannabinoid in marijuana after THC. In hemp, however, THC is only present in trace amounts. In other words, CBD oil will not get you high.

How CBD Interacts With Mammals
CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. As our environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to help keep us level.

The endocannabinoid system is found in all mammals, and is made up of millions of cannabinoid receptor sites located primarily throughout the brain and central nervous system (CB1 receptors) and immune system (CB2 receptors) that act in neural communication.

It’s clear that the endocannabinoid system is one of the most important regulatory systems in the human body, but most people do very little to support the health of this system, because cannabinoids have not been part of the average diet. This same line of thinking also applies to your pet’s body!

What Aare The Benefits Of CBD Oil For Pets?
Although the AVMA (American Veterinary Medical Association) has no official stance or approval concerning CBD oil as a nutritional supplement, many vets and pets owners are convinced that CBD oil can be taken for as a supplement to help many conditions their animals experience.

The cannabinoid CBD interacts with the receptors in the body and can help modulate things like nausea, general health, and much more. There are also no life-threatening side effects with proper serving usage, and no damage to the kidney, liver, or GI tract.

As with any medication, pet owners should consult their veterinarian first before treating their dog with CBD oil. You may need to seek out a veterinarian who has experience with pets being treated with cannabis oil to discuss proper serving size and reputable manufacturers.

Note: Although CBD hemp oil is beneficial to health, CBDedication.com does not make any medical claims based on the products we sell and should not be used with the intention of curing, or improving an illness.

With cannabidiol (CBD) in the media as much as it is these days, you may be asking; Why should I use CBD oil?

There are many benefits to taking CBD products, but the most exciting among them is that a CBD oil supplement helps augment the body’s naturally occurring endocannabinoids, increasing the body’s ability to promote homeostasis within its systems.

Cannabinoids are a class of active chemical compounds produced by the cannabis plant. These cannabinoids act on cannabinoid receptors located in our cells as part of the endocannabinoid system and alter the release of neurotransmitters in the brain. The endocannabinoid system predominantly consists of two endocannabinoid receptors: CB1, located in the central nervous system, and CB2, found throughout the peripheral nervous system.

There are over 100 presently discovered cannabinoids, which are largely responsible for the effects cannabis has on the body. Common cannabinoids include tetrahydrocannabinol (THC), cannabidiol (CBD), cannabinol (CBN), and cannabigerol (CBG). Cannabinoids work together with the body’s endocannabinoid system to regulate the body’s natural functions – including mood, sleep, appetite, and immune response.

Once the endocannabinoid system is supplemented in this way, it is able to function more efficiently, optimizing the body’s performance each day. Although it is not critical to supplement the endocannabinoid system daily, doing so may increase the effectiveness of CBD and the endocannabinoid system.

Because CBD oil products are categorized as supplements, we comply with the FDA’s DSHEA guidelines and cannot endorse any specific medical benefits of CBD or hemp oil. To further comply with FDA regulations, CBDedication.com does not list any Recommended Daily Intake (RDI) of our own, nor do we provide a Daily Value (%DV) for any of the products we sell. We encourage you to browse the thousands of reputable studies regarding CBD published online and talk with your doctor to see if a CBD supplement is right for you.

Note: Because each individual is unique, it’s  important to do research and speak with a physician or doctor regarding health-related questions or concerns that are specific to patient history. Although CBD hemp oil is beneficial to health, CBDedication.com does not make any medical claims based on the products we sell and should not be used with the intention of curing, or improving an illness.

A few short weeks ago, HempMeds® Mexico President Raul Elizalde addressed the United Nations and the World Health Organization (WHO) about CBD.

The Thirty-Ninth meeting of the Expert Committee on Drug Dependence was a five-day event in November 2017. The meeting took place for the ECDD to explore changes to the international scheduling of 16 different substances, including cannabidiol (CBD).

 

HISTORIC DAY FOR HEMPMEDS® AND CBD

The day was monumental for CBD, as the decision by the special committee could significantly influence CBD’s legality around the world and potentially impact the health options of millions.

At an open session on November 6, 2017, Raul spoke before the international officials about CBD’s benefits and its lack of psychoactivity. He urged the special committee to lift CBD’s internationally regulated status by considering it non-psychoactive and classifying it a nutritional supplement.

During his presentation to the committee at the U.N., Raul spread CBD awareness by sharing the story of his daughter Grace, Raul and his family were the first to sue the Mexican government for the right to import CBD oil into Mexico. He also shared the experiences of other families with CBD, and presented the results of recent studies on children using CBD products in Mexico.

 

RAUL’S ROAD

Raul’s story and journey to Geneva drew quite a bit of attention. Here is a collection of some of media articles and write-ups about Raul’s history-making journey.

HighTimes online’s A.J. Harrington wrote an article about HempMeds and Raul’s reasons for being a CBD champion. “He (Raul) was instrumental in the legalization of medical cannabis in Mexico, and his company (HempMeds®) produces the only cannabis medicine currently allowed by the Mexican government.”  https://hightimes.com/news/united-nations-decide-fate-cbd/

The MMJ Observer’s Steven Russel wrote this blog on Monday, November 6th, where he notes that “Dr. Stuart Titus, the CEO of HempMeds®, expressed that they are excited and honored to speak to United Nations leaders on an international stage about Cannabidiol as a supplement intended to maintain and enhance the well-being of millions.” https://www.mmjobserver.com/medical-marijuana-inc-otcmktsmjna-hempmeds-gets-attention-of-united-nations/29078/

The Latin American Heritage Tribune contributed this piece, that perfectly sums up Raul’s reasons for becoming a voice for CBD: “The father of a girl with severe epilepsy whose case paved the way for the legalization of medical marijuana in Mexico will appear before the World Health Organization on Monday to defend the use of a cannabis-derived compound as a treatment for seizures.”   http://www.laht.com/article.asp?ArticleId=2445772&CategoryId=14091